Completed Trials 2023  

Alopecia Areata – HZNP-DAX-201
Alopecia Areata – HZNP-DAX-201

A Phase 2A, Open Label, Proof-of-Concept Trial of Daxdilimab for the Treatment of Moderate-to-Severe Alopecia Areata Register Today!

Atopic Dermatitis – ACT17207
Atopic Dermatitis – ACT17207

A Phase 2, randomized, double-blind, placebo controlled, multicenter proof-of-concept study evaluating efficacy and safety of rilzabrutinib in adult patients with moderate-to-severe atopic dermatitis who are inadequate responders or intolerant to topical corticosteroids. Register Today!

Plaque Psoriasis – (ME3183-3)
Plaque Psoriasis – (ME3183-3)

Phase 2a Study to Assess the Efficacy and Safety of ME3183 Administered Orally in Subjects with Moderate to Severe Plaque Psoriasis Register Today!</a

Atopic Dermatitis (B7451015 extension of B7451050)
Atopic Dermatitis (B7451015 extension of B7451050)

A phase 3B randomized, double-blind, double-dummy, active controlled multi-center study assessing the efficacy and safety of Abrocitinib compared with Dupilumab in adult participants on background topical therapy with moderate to severe atopic dermatitis. Register Today!.

Plaque Psoriasis (CAIN2322)
Plaque Psoriasis (CAIN2322)

Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. It typically affects the outside of the elbows, knees or scalp, though it can appear on any location. Some...

Crohn’s Disease (M14-433/431)
Crohn’s Disease (M14-433/431)

Crohn’s disease is an inflammatory bowel disease (IBD). It causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by Crohn’s...

Endometriosis-Associated Pain (M14-702)
Endometriosis-Associated Pain (M14-702)

Endometriosis is an often times painful disorder in which tissue that normally lines the inside of your uterus, the endometrium, grows outside your uterus. The objective of this study is to evaluate safety and efficacy of...

Completed Trials 2022  

Osteoarthritis of the Knee (BP-2020-G001-P2)
Osteoarthritis of the Knee (BP-2020-G001-P2)

This trial is a Phase 2 Multicenter, Double-blind, Randomized, Parallel-Group, Vehicle- Controlled Study to Evaluate the Efficacy, Safety, and Local Tolerability of G001 in Patients with Osteoarthritis (OA) of the Knee. The objectives of this...

Atopic Dermatitis (I4V-MC-JAIX)
Atopic Dermatitis (I4V-MC-JAIX)

Atopic dermatitis (AD) is a pruritic, chronic or chronically relapsing, highly symptomatic inflammatory skin disease characterized by excessive T cell activation leading to significant skin infiltration by T cells and dendritic cells (Bieber 2010). Presentation...

Completed Trials 2021  

Ulcerative Colitis (ABI-M201-101)
Ulcerative Colitis (ABI-M201-101)

A randomized, double-blind, placebo-controlled, multi-center Phase 1b study to evaluate the safety, efficacy and microbiological response of orally administered ABI-M201 in subjects with mildly-to-moderately active Ulcerative Colitis with ongoing Mesalamine treatment. Register Today!

Type 2 Diabetes (I8F-MC-GPGM)
Type 2 Diabetes (I8F-MC-GPGM)

Efficacy and safety of LY3298176 once weekly versus Insulin Glargine in patients with Type 2 Diabetes and increased cardiovascular risk. Register Today!

Endometriosis (P19-933)
Endometriosis (P19-933)

Real-world experience of elagolix for the treatment of endometriosis in Canada: an observational cohort study (GRACE) Register Today!

Eczema in Adults & Adolescents (M16-813)
Eczema in Adults & Adolescents (M16-813)

Atopic dermatitis or eczema as it is commonly known, is a condition that makes your skin red and itchy. The disease is common in children but can also occur at any age. Eczema is a...

Asthma in Adults and Children (AV003 – MANDALA)
Asthma in Adults and Children (AV003 – MANDALA)

According to Asthma Canada, the medical definition of asthma is simple, but the condition itself is quite complex. Doctors define asthma as a “chronic inflammatory disease of the airway” that causes the following symptoms: –...

Pediatric Pneumococcal Vaccine (V114-031)
Pediatric Pneumococcal Vaccine (V114-031)

Pneumonia is inflammation of the lungs caused by bacteria, viruses, any in some cases, chemical irritants. It is a serious infection in which air sacs in the lungs fill with liquid making it difficult to...

Ulcerative Colitis (M14-234)
Ulcerative Colitis (M14-234)

The purpose of the study is to evaluate the safety and efficacy of ABT-494 for induction and maintenance therapy in subjects with moderately to severely active ulcerative colitis. Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) is an inflammatory...

Completed Trials 2020  

Single-use Testosterone in Healthy Participants (PK Study)
Single-use Testosterone in Healthy Participants (PK Study)

The purpose of this work is to investigate the dose-response curve for intranasal testosterone in healthy young men and women. A large body of evidence has investigated links between baseline levels of testosterone and individual...

Palmoplantar Psoriasis (ANB019-003)
Palmoplantar Psoriasis (ANB019-003)

A Phase II, randomized, placebo-controlled, double-blind, multiple dose study to evaluate the Efficacy and Safety of ANB019 in subjects with Palmoplantar Pustulosis. Register Today!

Osteoarthritis Knee Pain (ATB-346-P2B-DRF)
Osteoarthritis Knee Pain (ATB-346-P2B-DRF)

A double-blind, placebo-controlled, 4-arm, Phase 2B study to asses the efficacy and safety of a 14-Day dosing regimen of 3 doses of ATB-346 versus Placebo, orally administered once daily to male and female patients diagnosed...

Treatment of Alopecia Areata (B7981015)
Treatment of Alopecia Areata (B7981015)

According to Alopecia Areata Canada, alopecia is the loss or the absence of hair. Alopecia areata is an autoimmune disease in which the immune system, for unknown reasons, attacks the hair root and causes hair...

Completed Trials 2019  

Palmoplantar Pustulosis (RIST4721-201)
Palmoplantar Pustulosis (RIST4721-201)

According to the National Psoriasis Foundation, Palmoplantar Pustulosis is a disease that causes pustules, or blisters to form on the palms of the hand and soles of the feet. It commonly affects the base of...

Atopic Dermatitis/Eczema (I4V-MC-JAIW)
Atopic Dermatitis/Eczema (I4V-MC-JAIW)

Atopic dermatitis, better known as eczema, is a medical condition in which your skin becomes red and itchy. The condition is quite common in children, but can occur at any age. Eczema is a chronic,...

Hepatits B Vaccine (233961 Sci-B-Vac-002)
Hepatits B Vaccine (233961 Sci-B-Vac-002)

The primary objective of the study is to verify that the manufacturing equivalence of Sci-B-Vac™ is consistent and to compare the immunogenicity and safety of a three-dose regimen of Sci-B-Vac™ to a three-dose regimen of...

Hepatitis B Vaccine Study (Sci-B-Vac-001)
Hepatitis B Vaccine Study (Sci-B-Vac-001)

This study is a double-blind randomized controlled trial designed to establish the non-inferiority of Sci-B-Vac compared to Engerix-B® in adults ≥ 18 years old and the superiority of Sci-B-Vac™ compared to Engerix-B® in adults ≥...

Anemia in Renal Failure (AKB-6548-CI-0017)
Anemia in Renal Failure (AKB-6548-CI-0017)

When kidneys are diseased or damaged, they do not make enough EPO, a hormone produced by the kidney which aids in the production and formation of red blood cells in bone marrow. The bone marrow...

COPD (PT010005 “Pearl”)
COPD (PT010005 “Pearl”)

People with COPD usually have one or more of these symptoms: a cough that lasts a long time (longer than 3 months) a cough with mucus feeling short of breath lung infections (the flu, acute...

Ulcerative Colitis (UCO-3001)
Ulcerative Colitis (UCO-3001)

Ulcerative colitis is more localized in nature than Crohn’s disease. Typically, the disease affects the colon (large bowel) including the rectum and anus, and only invades the inner lining of bowel tissue. It almost always...

Crohn’s Disease (M14-115)
Crohn’s Disease (M14-115)

Crohn’s disease is an inflammatory bowel disease (IBD). It causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by Crohn’s...

Peripheral Artery Disease (COMPASS)
Peripheral Artery Disease (COMPASS)

A randomized controlled trial of rivaroxaban for the prevention of major cardiovascular events in patients with coronary or peripheral artery disease (COMPASS – Cardiovascular OutcoMes for People using Anticoagulation Strategies) Click here for more information....

Meningitis Vaccine (C0921003)
Meningitis Vaccine (C0921003)

Immunogenicity and safety study of 1 and 2 doses of GSK Biologicals’ meningococcal vaccine GSK134612 in toddlers, persistence up to 5 years after vaccination and co-administration with Pfizer’s pneumococcal vaccine Prevenar 13™. https://clinicaltrials.gov/ct2/show/NCT01939158?term=C0921003&rank=1 Register Today!

Completed Trials 2018  

Influenza Vaccine (CP-PRO-QVLP-012)
Influenza Vaccine (CP-PRO-QVLP-012)

Influenza (flu) is caused by a virus (a germ) and is spread by contact with nasal (nose) and oral (mouth) secretions. Symptoms include sudden fever, headache, chills, muscle aches, and cough. The main strategy of...

Cardiovascular (CIRT)
Cardiovascular (CIRT)

CIRT will examine if taking low-dose methotrextate (LDM) once a week will reduce inflammation and decrease the risk for heart attacks, strokes, and death among men and women who have had a heart attack or...

Type II Diabetes in Renal Failure (M11-352)
Type II Diabetes in Renal Failure (M11-352)

Kidneys are remarkable organs. Inside them are millions of tiny blood vessels that act as filters. Their job is to remove waste products from the blood. Sometimes this filtering system breaks down. Diabetes can damage...

Completed Trials 2017  

Crohn’s (20110232)
Crohn’s (20110232)

The purpose of the study is to find out more about a protien, AMG 181, in people with moderate to severe Crohn’s disease. This study will evaluate whether the protein prevents immune cells from migrating...

Ulcerative Colitis (APD334-005)
Ulcerative Colitis (APD334-005)

The purpose of this extension study is to find out more about the safety and efficacy of APD334 for the treatment of moderately to severely active ulcerative colitis.  APD334 is an experimental drug which has...

Boostrix Vaccine 6 month (201334)
Boostrix Vaccine 6 month (201334)

The purpose of this study is to assess the immunogenicity and safety of the Infanrix hexa booster dose given at 12-18 months of age to infants who received primary vaccination at 6-12 weeks. All infants...

Boostrix Vaccine 2 Month (201330)
Boostrix Vaccine 2 Month (201330)

The purpose of this study is to evaluate the immunogenicity and safety of GSK Biologicals’ Infanrix hexa, given in the primary vaccination schedule to infants born to pregnant women who participated in study 116945 [DTPA...

COPD (PT009002 “Pearl”)
COPD (PT009002 “Pearl”)

People with COPD usually have one or more of these symptoms: a cough that lasts a long time (longer than 3 months) a cough with mucus feeling short of breath lung infections (the flu, acute...

Overactive Bladder (178-MA-1005)
Overactive Bladder (178-MA-1005)

Overactive Bladder (OAB) is a frequent condition affecting older adults and the urinary frequency and urgency associated with the condition are often highly debilitating. In addition, OAB related urinary incontinence has been associated with other...

Uterine Fibroids (M12-817)
Uterine Fibroids (M12-817)

The purpose of this study is to determine the safety of elagolix and how elagolix works when compared to placebo in reducing heavy menstrual bleeding, the major symptom of uterine fibroids. Register Today!

Boostrix Vaccine (Pregnant Women)
Boostrix Vaccine (Pregnant Women)

GSK Biologicals’ reduced-antigen-content dTpa vaccine, Boostrix, is a combination booster vaccine (a vaccine against more than one disease combined into one shot) indicated for individuals from the age of four years onwards against diphtheria, tetanus...

Diabetes (DIA-3008 “Canvas”)
Diabetes (DIA-3008 “Canvas”)

Over the past decades, the incidence of type 2 diabetes mellitus (T2DM) has been rapidly rising worldwide, driven primarily by an increasing incidence of obesity and sedentary lifestyles. Patients with T2DM can develop severe microvascular...

Ulcerative Colitis (ADP334-003)
Ulcerative Colitis (ADP334-003)

Ulcerative colitis is more localized in nature than Crohn’s disease. Typically, the disease affects the colon (large bowel) including the rectum and anus, and only invades the inner lining of bowel tissue. It almost always...

Crohn’s Disease (M13-740)
Crohn’s Disease (M13-740)

Crohn’s disease is an inflammatory bowel disease (IBD). It causes inflammation of the lining of your digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by Crohn’s...

COPD “Pearl” (PT010006)
COPD “Pearl” (PT010006)

People with COPD usually have one or more of these symptoms: a cough that lasts a long time (longer than 3 months) a cough with mucus feeling short of breath lung infections (the flu, acute...

Female low sexual desire – Reconnect (BMT-302)
Female low sexual desire – Reconnect (BMT-302)

Hypoactive sexual desire disorder (HSDD) refers to a woman’s chronic or ongoing lack of interest in sex, to the point that it causes her personal distress or problems in her relationships. To evaluate the efficacy...

COPD (CTT116855)
COPD (CTT116855)

People with COPD usually have one or more of these symptoms: a cough that lasts a long time (longer than 3 months) a cough with mucus feeling short of breath lung infections (the flu, acute...

Crohn’s Extension Study (M14-347)
Crohn’s Extension Study (M14-347)

The primary objective of this study is to evaluate the long-term efficacy, safety, and tolerability of repeated administration of adalimumab in subjects with Crohn’s disease who participated in and successfully completed Study M14-115. The secondary...

Completed Trials 2016  

Effects of movies on testosterone (men 18-35)
Effects of movies on testosterone (men 18-35)

Another great study with Nipissing University evaluating the effects of viewing sexually explicit movies vs non-sexually explicit movies on male testosterone levels. For men aged 18-35. Register Today!

Plaque Psoriasis (CAIN457A2322)
Plaque Psoriasis (CAIN457A2322)

Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. It typically affects the outside of the elbows, knees or scalp, though it can appear on any location. Some...

Diabetes
Diabetes

A phase III randomised, double-blind, active-controlled parallel group efficacy and safety study of BI 10773 compared to glimepiride administered orally during 104 weeks in patients with type 2 diabetes mellitus and insufficient glycaemic control despite...

Completed Trials 2015  

Andro Study
Andro Study

Effects of testosterone on face perception, risk-taking, and decision-making An exciting Study with Nipissing University for men aged 18-35. A one visit study on the effects of topical testosterone on face perception, risk taking and...

Moderate to severe COPD
Moderate to severe COPD

A Randomized, Blinded, Double-dummy, Parallel-group Study to Evaluate the Efficacy and Safety of Umeclidinium (UMEC) 62.5 mcg compared with Tiotropium 18 mcg in Subjects with Chronic Obstructive Pulmonary Disease (COPD). Register Today!

Plaque Psoriasis (W14-406)
Plaque Psoriasis (W14-406)

Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. It typically affects the outside of the elbows, knees or scalp, though it can appear on any location. Some...

Plaque Psoriasis (20101177)
Plaque Psoriasis (20101177)

Psoriasis is an autoimmune disease that causes raised, red, scaly patches to appear on the skin. It typically affects the outside of the elbows, knees or scalp, though it can appear on any location. Some...

RSV Vaccine (RSV_P_101)
RSV Vaccine (RSV_P_101)

RSV can cause serious illness. It causes infection of the lungs and breathing passages and is a major cause of respiratory illness in young children. RSV is a virus that can make anyone sick but...

Shingles Vaccine
Shingles Vaccine

Immunogenicity and safety study of GSK Biologicals’ Herpes Zoster vaccine GSK1437173A when co-administered with Pneumovax 23™ in adults aged 50 years and older. Register Today!

Idiopathic Constipation
Idiopathic Constipation

A Randomized, 12-Week, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Plecanatide (3.0 and 6.0 mg) in Patients with Chronic Idiopathic Constipation Trial. Register Today!

Ulcerative Colitis
Ulcerative Colitis

A Phase 2b, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-response Study Evaluating the Efficacy and Safety of JNJ-54781532 in Subjects with Moderately to Severely Active Ulcerative Colitis. Register Today!

Plaque Psoriasis
Plaque Psoriasis

A Phase 3 Study to Evaluate the Efficacy, Safety, and Effect of Withdrawal and Retreatment With Brodalumab in Subjects With Moderate to Severe Plaque Psoriasis: AMAGINE-1. Register Today!

Plaque Psoriasis
Plaque Psoriasis

A Phase 3 Study to Evaluate the Efficacy and Safety of Induction and Maintenance Regimens of Brodalumab Compared With Placebo and Ustekinumab in Subjects With Moderate to Severe Plaque Psoriasis: AMAGINE-2. Register Today!

Diabetes with Cardiovascular Risk
Diabetes with Cardiovascular Risk

A Randomized, Multicenter, Double-Blind, Parallel, Placebo-Controlled Study Of The Effects Of JNJ-28431754 On Cardiovascular Outcomes In Adult Subjects With Type 2 Diabetes Mellitus. Register Today!

Completed Trials 2014  

HPV Vaccine Study
HPV Vaccine Study

A Phase IIIb open-label, randomised, multi-centre primary immunization study to evaluate the immunogenicity and safety of GSK Biologicals’ HPV-16/18 L1 VLP AS04 vaccine when administered intramuscularly according to alternative 2-dose schedules in 9 – 14...

Diabetes Medication with Implantable Device Study
Diabetes Medication with Implantable Device Study

A Phase 3, Randomized, Active Comparator, Double-Blind, Multi-Center Study to Compare the Efficacy, Safety and Tolerability of ITCA 650 to Sitagliptin as Add-on Therapy to Metformin in Patients with Type 2 Diabetes. Register Today!

Meningitis B Vaccine
Meningitis B Vaccine

A Phase 3, Randomized, Active-Controlled, Observer-Blinded Trial To Assess The Lot Consistency, Safety, Tolerability, And Immunogenicity Of A Meningococcal Serogroup B Bivalent Rlp2086 Vaccine In Healthy Subjects Aged 10 To <19 Years. Register Today!

H7N1 Pandemic Influenza Vaccine (Older Adult)
H7N1 Pandemic Influenza Vaccine (Older Adult)

A phase II observer-blind, randomized, controlled, multi-center trial to evaluate the safety and immunogenicity of different formulations of monovalent Influenza A/mallard/Netherlands/12/2000 NIBRG-63 (H7N1) vaccine manufactured in Quebec, Canada with AS03 adjuvant, given as a two-dose...

H7N1 Pandemic Influenza Vaccine (Adults)
H7N1 Pandemic Influenza Vaccine (Adults)

A phase I/II single-blind, randomized, controlled, multi-center trial to evaluate the safety and immunogenicity of different formulations of monovalent Influenza A/mallard/Netherlands/12/2000 NIBRG-63 (H7N1) vaccine manufactured in Quebec, Canada with and without AS03 adjuvant, given as...

Moderate to Severe COPD Treatment
Moderate to Severe COPD Treatment

Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase IV Study to Evaluate the Effect of Aclidinium Bromide on Long-Term Cardiovascular Safety and COPD Exacerbations in Patients with Moderate to Very Severe COPD. Register Today!

Pediatric influenza vaccine
Pediatric influenza vaccine

A Phase III, Stratified, Randomized, Observer Blind, Controlled, Multicenter Clinical Study to Evaluate the Safety, Immunogenicity and Efficacy of an Adjuvanted Quadrivalent Subunit Influenza Virus Vaccine Compared to Non-Adjuvanted Comparator Influenza Vaccine in Children ≥6...

Non-cancer pain
Non-cancer pain

Phase 3, randomized, double-blind, active-controlled, parallel arm study of PRC-062 (hydromorphone/naloxone controlled release capsules) in patients with chronic non-cancer pain. To see if IP is as effective as hydromorph contin. Register Today!

Atrial Fibrillation
Atrial Fibrillation

A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Multicenter, Multi-National Study For Evaluation Of Efficacy And Safety Of Du-176b Versus Warfarin In Subjects With Atrial Fibrillation – Effective Anticoagulation With Factor Xa Next Generation In...

Diabetes
Diabetes

A phase III, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of the fixed dose combination of Empagliflozin 10 mg/Linagliptin 5 mg compared with Empagliflozin 10 mg alone and the efficacy...

Diabetes
Diabetes

A 24-week, randomized, double-blind, active-controlled, parallel group trial to assess the superiority of oral linagliptin and metformin compared to linagliptin monotherapy in newly diagnosed, treatmentnaïve, uncontrolled Type 2 Diabetes Mellitus patients. Register Today!

Gout
Gout

A Phase 3 Randomized, Double-Blind, Multicenter, Placebo-Controlled, Combination Study to Evaluate the Efficacy and Safety of Lesinurad and Allopurinol Compared to Allopurinol Alone in Subjects with Gout who have had an Inadequate Hypouricemic Response to...

Seasonal Influenza Vaccine
Seasonal Influenza Vaccine

A Phase III, double-blind, randomised, controlled, multi-country, multi-centre study to evaluate the immunogenicity and safety of GSK Biologicals’ quadrivalent influenza vaccine candidate, GSK2282512A (FLU Q-QIV), compared to GSK Biologicals’ trivalent influenza vaccine Fluarix®, administered intramuscularly...